Journal: Cancer Cell International

Article Title: A pan-cancer analysis of molecular characteristics and oncogenic role of gasdermins

doi: 10.1186/s12935-022-02483-4

Figure Lengend Snippet: The expression of GSDM family genes. A Box plots represent the relative expression of GSDM genes in pan-cancer. B Heatmap showing differential expression of GSDM genes across cancer types. C Matrix graph of Pearson’s correlation of GSDM genes expression in pan-cancer. D – I Box plots represented the differential expression of six GSDM genes between tumor and normal tissue. J Methylation difference between tumor and paired normal tissue. P value was adjusted by FDR, FDR < = 0.05 was considered as significant. Only significant results were shown as bubble plots. K Pearson’s Product-moment Correlation between GSDM genes expression and corresponding gene methylation. P-value was adjusted by FDR and genes with FDR < = 0.05 will be showed

Article Snippet: The correlated genes of GSDM family members were determined by the Pearson’s Product-moment Correlation test in colorectal cell lines based on Broad Institute Cancer Cell Line Encyclopedia (CCLE) dataset.

Techniques: Expressing, Quantitative Proteomics, Methylation

Journal: Cancer Cell International

Article Title: A pan-cancer analysis of molecular characteristics and oncogenic role of gasdermins

doi: 10.1186/s12935-022-02483-4

Figure Lengend Snippet: GSDM family was involved in promoting metastasis and angiogenesis of colorectal cancer. A These three-circle Venn diagrams showed the interaction between the correlated genes of GSDMA, DSDMB and GSDME. These four-circle Venn diagrams showed the interaction between the correlated genes of GSDMA, DSDMB, GSDME and GSDMD. Notice that there was no or almost no interaction between some groups. The correlated genes of GSDM family members were determined by the Pearson’s Product-moment Correlation test in colorectal cell lines based on Broad Institute Cancer Cell Line Encyclopedia (CCLE) dataset. GSDMA/B/D/E cor (+)/(−) denoted the genes positively/negatively significantly (P < 0.05) correlated with GSDMA/B/D/E. The GO enrichment analysis was performed on the genes correlated with all the four GSDM genes. B GSDME expression was positively correlated with the expression of CD31 and CD34 based on TCGA-COAD dataset analysis. C Increased expression of GSDME provided endothelial development advantage based on Gene Set Enrichment Analysis (GSEA). D Violin plot revealed that GSDME expression was correlated with stage of CRC

Article Snippet: The correlated genes of GSDM family members were determined by the Pearson’s Product-moment Correlation test in colorectal cell lines based on Broad Institute Cancer Cell Line Encyclopedia (CCLE) dataset.

Techniques: Expressing

Journal: ACS Omega

Article Title: Exploring the Impact of Naphthalene (Polycyclic Aromatic Hydrocarbons) on Anabas testudineus (Bloch) through Dose-Specific Bioenzymological Analysis

doi: 10.1021/acsomega.3c08535

Figure Lengend Snippet: Illustration of Pearson product-moment correlations between variable pairs, quantifying the linear relationship strength with coefficients ranging from −1 to +1. ( P -value below 0.05 indicates a significant nonzero correlation at a 95.0% confidence level. Notably, the following variable pairs exhibit P -values below 0.05: Tr and Sc, Tr and Sk, Tr and Va, Sc and Sk, Sc and Va, Sk and Va.)

Article Snippet: The Pearson product-moment correlation coefficient gauges the strength and direction of the relationship between two variables, seeking to establish a best-fit line through their data (Statgraphics Centurion XIX, The Plains, Virginia, United States).

Techniques: